Let's say you had to start from utter scratch right now and build a system... what would your choices be?

It seems we're getting to the point where with some audiophile level active speakers setup and just a SB3 or Transporter and some very good cabling some awesome results can be achieved. I don't know of anyone that has such a system yet, but I'd be very curious. And tempted.

Sugestions, experiences? I will be dividing my life between 2 continents soon, and would like a high quality audio system in both places. One's covered with what I have, the other one will be built around a SB3 or Transporter.